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| Core Runes for all Classes | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Vigor | +30 Health | +41 Health | +50 Health |
| Nightfall Runes for all Classes | |
| Rune of Vitae Health +10 |
Rune of Attunement Energy +2 |
| Rune of Recovery Reduces dazed duration on you by 20% Reduces deep wound duration on you by 20% |
Rune of Restoration Reduces bleeding duration on you by 20% Reduces crippled duration on you by 20% |
| Rune of Clarity Reduces blind duration on you by 20% Reduces weakness duration on you by 20% |
Rune of Purity Reduces disease duration on you by 20% Reduces poison duration on you by 20% |

| Assassin Runes
As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Critical Strikes | +1 Critical Strikes | +2 Critical Strikes -35 Health |
+3 Critical Strikes -75 Health |
| Dagger Mastery | +1 Dagger Mastery | +2 Dagger Mastery -35 Health |
+3 Dagger Mastery -75 Health |
| Deadly Arts | +1 Deadly Arts | +2 Deadly Arts -35 Health |
+3 Deadly Arts -75 Health |
| Shadow Arts | +1 Shadow Arts | +2 Shadow Arts -35 Health |
+3 Shadow Arts -75 Health |

| Dervish Runes | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Earth Prayers | +1 Earth Prayers | +2 Earth Prayers -35 Health |
+3 Earth Prayers -75 Health |
| Mysticism | +1 Mysticism | +2 Mysticism -35 Health |
+3 Mysticism -75 Health |
| Scythe Mastery | +1 Scythe Mastery | +2 Scythe Mastery -35 Health |
+3 Scythe Mastery -75 Health |
| Wind Prayers | +1 Wind Prayers | +2 Wind Prayers -35 Health |
+3 Wind Prayers -75 Health |

| Elementalist Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Air Magic | +1 Air Magic | +2 Air Magic -35 Health |
+3 Air Magic -75 Health |
| Earth Magic | +1 Earth Magic | +2 Earth Magic -35 Health |
+3 Earth Magic -75 Health |
| Energy Storage | +1 Energy Storage | +2 Energy Storage -35 Health |
+3 Energy Storage -75 Health |
| Fire Magic | +1 Fire Magic | +2 Fire Magic -35 Health |
+3 Fire Magic -75 Health |
| Water Magic | +1 Water Magic | +2 Water Magic -35 Health |
+3 Water Magic -75 Health |

| Mesmer Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Domination | +1 Domination | +2 Domination -35 Health |
+3 Domination -75 Health |
| Fast Casting | +1 Fast Casting | +2 Fast Casting -35 Health |
+3 Fast Casting -75 Health |
| Illusion | +1 Illusion | +2 Illusion -35 Health |
+3 Illusion -75 Health |
| Inspiration | +1 Inspiration | +2 Inspiration -35 Health |
+3 Inspiration -75 Health |

| Monk Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Divine Favor | +1 Divine Favor | +2 Divine Favor -35 Health |
+3 Divine Favor -75 Health |
| Healing Prayers | +1 Healing Prayers | +2 Healing Prayers -35 Health |
+3 Healing Prayers -75 Health |
| Protection Prayers | +1 Protection Prayers | +2 Protection Prayers -35 Health |
+3 Protection Prayers -75 Health |
| Smiting Prayers | +1 Smiting Prayers | +2 Smiting Prayers -35 Health |
+3 Smiting Prayers -75 Health |

| Necromancer Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Blood Magic | +1 Blood Magic | +2 Blood Magic -35 Health |
+3 Blood Magic -75 Health |
| Curses | +1 Curses | +2 Curses -35 Health |
+3 Curses -75 Health |
| Death Magic | +1 Death Magic | +2 Death Magic -35 Health |
+3 Death Magic -75 Health |
| Soul Reaping | +1 Soul Reaping | +2 Soul Reaping -35 Health |
+3 Soul Reaping -75 Health |

| Paragon Runes | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Command | +1 Command | +2 Command -35 Health |
+3 Command -75 Health |
| Leadership | +1 Leadership | +2 Leadership -35 Health |
+3 Leadership -75 Health |
| Motivation | +1 Motivation | +2 Motivation -35 Health |
+3 Motivation -75 Health |
| Spear Mastery | +1 Spear Mastery | +2 Spear Mastery -35 Health |
+3 Spear Masterys -75 Health |

| Ranger Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Beastmastery | +1 Beastmastery | +2 Beastmastery -35 Health |
+3 Beastmastery -75 Health |
| Expertise | +1 Expertise | +2 Expertise -35 Health |
+3 Expertise -75 Health |
| Marksmanship | +1 Marksmanship | +2 Marksmanship -35 Health |
+3 Marksmanship -75 Health |
| Wilderness Survival | +1 Wilderness Survival | +2 Wilderness Survival -35 Health |
+3 Wilderness Survival -75 Health |

| Ritualist Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Channeling Magic | +1 Channeling Magic | +2 Channeling Magic -35 Health |
+3 Channeling Magic -75 Health |
| Communing | +1 Communing | +2 Communing -35 Health |
+3 Communing -75 Health |
| Restoration Magic | +1 Restoration Magic | +2 Restoration Magic -35 Health |
+3 Restoration Magic -75 Health |
| Spawning Power | +1 Spawning Power | +2 Spawning Power -35 Health |
+3 Spawning Power -75 Health |

| Warrior Runes As of 6/1/06 update, the Health penalty on Major runes was reduced to 35. | |||
| Attribute | Minor![]() |
Major![]() |
Superior![]() |
| Absorption | Reduces damage from physical attacks by 1 | Reduces damage from physical attacks by 2 | Reduces damage from physical attacks by 3 |
| Axe Mastery | +1 Axe Mastery | +2 Axe Mastery -35 Health |
+3 Axe Mastery -75 Health |
| Hammer Mastery | +1 Hammer Mastery | +2 Hammer Mastery -35 Health |
+3 Hammer Mastery -75 Health |
| Strength | +1 Strength | +2 Strength -35 Health |
+3 Strength -75 Health |
| Swordsmanship | +1 Swordsmanship | +2 Swordsmanship -35 Health |
+3 Swordsmanship -75 Health |
| Tactics | +1 Tactics | +2 Tactics -35 Health |
+3 Tactics -75 Health |
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